Whole-brain serial-section electron microscopy in larval zebrafish

Hildebrand DGC, Cicconet M, Torres RM, Choi W, Quan TM, Moon J, Wetzel AW, Scott Champion A, Graham BJ, Randlett O, Plummer GS, Portugues R, Bianco IH, Saalfeld S, Baden AD, Lillaney K, Burns R, Vogelstein JT, Schier AF, Lee WA, Jeong WK, Lichtman JW, Engert F.

Joshua Sanes wins 2017 Gruber Neuroscience Prize

Congratulations to Josh, who won "for his pioneering and inspiring work on synapse formation."

Cell diversity and network dynamics in photosensitive human brain organoids

Quadrato G, Nguyen T, Macosko EZ, Sherwood JL, Min Yang S, Berger DR, Maria N, Scholvin J, Goldman M, Kinney JP, Boyden ES, Lichtman JW, Williams ZM, McCarroll SA, Arlotta P.

The genetic basis of parental care evolution in monogamous mice

Bendesky A, Kwon YM, Lassance JM, Lewarch CL, Yao S, Peterson BK, He MX, Dulac C, Hoekstra HE.

Somatosensory Cortex Plays an Essential Role in Forelimb Motor Adaptation in Mice

Mackenzie Weygandt Mathis, Alexander Mathis, Naoshige Uchida

Some Recent Publications

Topics range from plasticity in GABA circuits to how worms eat.

What We Do

Researchers in the Center for Brain Science (CBS) are discovering how brain circuits give rise to computations that underlie thought and behavior. We are determining the structure and function of neural circuits; investigating how these circuits govern behavior and vary between individuals; learning how they change during development and aging; and deepening our understanding of what is amiss in neurological and psychiatric disorders, and how to address these pathologies. To accomplish this mission, CBS brings neuroscientists together with physical scientists and engineers to develop and deploy new tools for neuroscience. Headquartered in the new Northwest Building on Oxford Street in Cambridge, CBS has strong links throughout the neuroscience community at Harvard University. Members are drawn from the Faculty of Arts and Sciences, the Harvard Medical School, the School of Engineering and Applied Sciences, and the Harvard-affiliated hospitals.

Neuroengineering: what tools we need

Neuroimaging: what underlies our thoughts

Light Microscopy: what the brain looks like 

Electron Microscopy: what is the brain's nanostructure

Connectome Project: how the brain is wired

Swartz Program: how do we understand brain function

Education: what training we need