Dopamine signals as temporal difference errors: recent advances.

Clara Kwon Starkweather, Naoshige Uchida

Increase in Seizure Susceptibility After Repetitive Concussion Results from Oxidative Stress, Parvalbumin-Positive Interneuron Dysfunction and Biphasic Increases in Glutamate/GABA Ratio

Paul MacMullin, Nathaniel Hodgson, Ugur Dama,r Henry Hing, Cheong Lee,Mustafa Q Hameed, Sameer C Dhamne, Damon Hyde , Grace M Conley, Nicholas Morriss , Jianhua Qiu, Rebekah Mannix, Takao K Hensch, Alexander Rotenberg

An evolutionarily acquired microRNA shapes development of mammalian cortical projections

Jessica L Diaz, Verl B Siththanandan, Victoria Lu, Nicole Gonzalez-Nava, Lincoln Pasquina, Jessica L MacDonald, Mollie B Woodworth, Abdulkadir Ozkan, Ramesh Nair, Zihuai He, Vibhu Sahni, Peter Sarnow, Theo D Palmer, Jeffrey D Macklis, Suzanne Tharin

Global regulatory features of alternative splicing across tissues and within the nervous system of C. elegans

Bina Koterniak, Pallavi P Pilaka , Xicotencatl Gracida, Lisa-Marie Schneider, Iva PritiĊĦanac, Yun Zhang, John A Calarco

The rational use of causal inference to guide reinforcement learning strengthens with age

Alexandra O Cohen, Kate Nussenbaum, Hayley M Dorfman, Samuel J Gershman, Catherine A Hartley

Rods Contribute to Visual Behavior in Larval Zebrafish

P Venkatraman, I Mills-Henry, K Ramaswamy Padmanadhan P Pascuzzi, M Hassan, J Zhang, X. Zhang, P Ma, C Pui Pang,  J E Dowling, M Zhang, Y Fai Leung



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What We Do

Researchers in the Center for Brain Science (CBS) are discovering how brain circuits give rise to computations that underlie thought and behavior. We are determining the structure and function of neural circuits; investigating how these circuits govern behavior and vary between individuals; learning how they change during development and aging; and deepening our understanding of what is amiss in neurological and psychiatric disorders, and how to address these pathologies. To accomplish this mission, CBS brings neuroscientists together with physical scientists and engineers to develop and deploy new tools for neuroscience. Headquartered in the new Northwest Building on Oxford Street in Cambridge, CBS has strong links throughout the neuroscience community at Harvard University. Members are drawn from the Faculty of Arts and Sciences, the Harvard Medical School, the School of Engineering and Applied Sciences, and the Harvard-affiliated hospitals.

Neuroengineering: what tools we need

Neuroimaging: what underlies our thoughts

Light Microscopy: what the brain looks like 

Electron Microscopy: what is the brain's nanostructure

Connectome Project: how the brain is wired

Swartz Program: how do we understand brain function

Education: what training we need